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N-051

Supelco

Nalbuphine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formule empirique (notation de Hill):
C21H28ClNO4
Numéro CAS:
23277-43-2
Poids moléculaire :
393.90
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

certified reference material

Forme

liquid

Caractéristiques

Snap-N-Spike®/Snap-N-Shoot®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

Concentration

1.0 mg/mL in methanol (as free base)

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

forensics and toxicology

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES 

Cl.O[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC6CCC6)c45

InChI

1S/C21H27NO4.ClH/c23-14-5-4-13-10-16-21(25)7-6-15(24)19-20(21,17(13)18(14)26-19)8-9-22(16)11-12-2-1-3-12;/h4-5,12,15-16,19,23-25H,1-3,6-11H2;1H/t15-,16+,19-,20-,21+;/m0./s1

Clé InChI

YZLZPSJXMWGIFH-BCXQGASESA-N

Informations sur le gène

human ... OPRD1(4985) , OPRK1(4986) , OPRM1(4988)

Description générale

A Snap-N-Spike® reference solution applicable for use in urine drug testing, pain prescription monitoring, clinical toxicology, forensic analysis, or pharmaceutical research by LC-MS/MS or GC/MS. Nalbuphine is a semisynthetic opioid analgesic sold under the trade name Nubain®. This painkiller is prescribed for the relief of moderate to severe pain.

Application


  • Development of a Thin-Layer Chromatography-Enzymatic Test Combination Method for the Isolation of α-Glucosidase Inhibitors From Thymelaea hirsuta.: Abid et al. (2022) combined thin-layer chromatography and enzymatic tests using Silica gel 60 TLC plates to isolate α-glucosidase inhibitors from Thymelaea hirsuta, showcasing a novel method for biochemical studies (Abid et al., 2022).

  • HPLC-UV and TLC-Densitometry Methods for Simultaneous Determination of Sofosbuvir and Daclatasvir: Application to Darvoni Tablet.: Fayed et al. (2022) utilized Silica gel 60 TLC plates in their TLC-densitometry method for the simultaneous determination of sofosbuvir and daclatasvir in pharmaceutical tablets, demonstrating the method′s application in pharmaceutical analysis (Fayed et al., 2022).


Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Nubain is a registered trademark of Endo Pharmaceuticals Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Juan F De La Mora-González et al.
Middle East journal of anaesthesiology, 21(4), 553-557 (2013-01-19)
Dexmedetomidine has demonstrated to be useful in several clinical fields due to its respiratory safety and cardiovascular stability. We undertook this study to determine its usefulness in plastic surgery. Sixty patients were divided into two parallel groups. A group received
Jason S Clark et al.
Veterinary ophthalmology, 14(6), 358-364 (2011-11-05)
To evaluate the effectiveness of topical nalbuphine or oral tramadol in the treatment of corneal pain in dogs. Fourteen male Beagle dogs. Dogs were divided into three treatment groups and sedated with dexmedetomidine (5 μ/kg IV). A 4 mm corneal
David Sanchez-Migallon Guzman et al.
American journal of veterinary research, 72(6), 736-740 (2011-06-02)
To evaluate the antinociceptive effects and duration of action of nalbuphine HCl administered IM on thermal thresholds in Hispaniolan Amazon parrots (Amazona ventralis). 14 healthy adult Hispaniolan Amazon parrots of unknown sex. 3 doses of nalbuphine (12.5, 25, and 50
S Sultana et al.
Drug research, 63(5), 224-227 (2013-03-15)
The interaction of nalbuphine hydrochloride with calf thymus deoxyribonucleic acid was investigated by absorption and fluorescence titration techniques. Hypochromic effect was observed in the absorption spectra of nalbuphine. The fluorescence quenching of nalbuphine by DNA was found to be static
Robert Gear et al.
PloS one, 8(1), e50169-e50169 (2013-01-24)
Nalbuphine, an agonist-antagonist kappa-opioid, produces brief analgesia followed by enhanced pain/hyperalgesia in male postsurgical patients. However, it produces profound analgesia without pain enhancement when co-administration with low dose naloxone. To examine the effect of nalbuphine or nalbuphine plus naloxone on
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