Accéder au contenu
Merck
Toutes les photos(2)

Key Documents

View All Documentation

840514C

Avanti

16:0-18:1 Phosphatidylethanol

Avanti Research™ - A Croda Brand 840514C

Synonyme(s) :

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol (sodium salt)

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(2)

About This Item

Formule empirique (notation de Hill):
C39H74NaO8P
Numéro CAS:
322647-55-2
Poids moléculaire :
724.96
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

liquid

Conditionnement

pkg of 1 × 2.5 mL (840514C-25mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 840514C

Concentration

10 mg/mL (840514C-25mg)

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[H][C@@](COP([O-])(OCC)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

Description générale

Phosphatidylethanol (PEth) is a phospholipid, that is generated in the the presence of ethanol in cell membranes. PEths like PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 possesses a common phosphoethanol head. Two fatty acid chains of variable length and degree of saturation are bound to this head group. It is widely distributed in gram-positive organisms.
Phosphatidylethanol (PEth) represents a group of glycerophospholipid homologues generated by substitution of ethanol for the lipid headgroup by the phospholipase D enzyme. Since the formation of PEth is specifically dependent on ethanol, the diagnostic specificity of PEth as an alcohol biomarker is theoretically 100%.

Application

16:0-18:1 Phosphatidylethanol is suitable for use in the preparation of liposomes used for permeability studies.

Actions biochimiques/physiologiques

Phosphatidylethanols (PEths) serves as crucial biomarkers of alcohol consumption.

Conditionnement

5 mL Clear Glass Sealed Ampule (840514C-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogrammes

Skull and crossbonesHealth hazard
GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organes cibles

Central nervous system, Liver,Kidney

Classe de danger pour l'eau (WGK)

WGK 3

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Les clients ont également consulté

Slide 1 of 5

1 of 5

18:1 Phosphatidylmethanol 1,2-dioleoyl-sn-glycero-3-phosphomethanol (sodium salt), powder

Avanti

840420P

18:1 Phosphatidylmethanol

16:0-d31-18:1 PE 1-palmitoyl-d31-2-oleoyl-sn-glycero-3-phosphoethanolamine, chloroform

Avanti

860374C

16:0-d31-18:1 PE

Protoveratrine A phyproof® Reference Substance

PHL89336

Protoveratrine A

16:0-18:2 PE 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine, chloroform

Avanti

850756C

16:0-18:2 PE

Veratridine ≥90% (HPLC), powder

Sigma-Aldrich

V5754

Veratridine

Interactions of oritavancin, a new lipoglycopeptide derived from vancomycin, with phospholipid bilayers: effect on membrane permeability and nanoscale lipid membrane organization
Domenech O, et al.
Biochimica et Biophysica Acta - Biomembranes, 1788(9), 1832-1840 (2009)
Alexandra Schröck et al.
Bioanalysis, 6(17), 2285-2294 (2014-11-11)
For early diagnosis and therapy of alcohol-related disorders, alcohol biomarkers are highly valuable. Concerning specificity, indirect markers can be influenced by nonethanol-related factors, whereas direct markers are only formed after ethanol consumption. Sensitivity of the direct markers depends on cut-offs
Anders Isaksson et al.
Drug testing and analysis, 3(4), 195-200 (2011-03-26)
Phosphatidylethanol (PEth) represents a group of glycerophospholipid homologues where ethanol by phospholipase D has been bound at the position that normally contains an amino-alcohol. Since the formation of PEth is specifically dependent on ethanol, the diagnostic specificity of PEth as
David Wensbo Posaric et al.
Analytical and bioanalytical chemistry, 406(19), 4735-4744 (2014-05-29)
Various phosphatidylethanol (PEth) derivatives, the corresponding reversed positional isomers (RPI-PEths), lyso-PEth-16:0, and penta-deuterium-labeled PEth analogs (d5-PEths), were synthesized by enzyme-independent synthetic routes. A general solvent system consisting of a mixture of acetone-d6 and methanol-d4 (97:3; v/v) was found to provide
The detection of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol and ethyl glucuronide in human umbilical cord
Jones J, et al.
American Journal of Analytical Chemistry, 3(12), 800-800 (2012)
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique