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K2755

Sigma-Aldrich

2-Keto-3-deoxyoctonate ammonium salt

≥97%

Synonyme(s) :

3-Deoxyoctulosonic acid, KDO

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About This Item

Formule linéaire :
C8H14O8 · NH3
Numéro CAS:
103404-70-2
Poids moléculaire :
255.22
Numéro MDL:
MFCD00057549
Code UNSPSC :
12352100
ID de substance PubChem :
57654316
Nomenclature NACRES :
NA.22

Pureté

≥97%

Forme

powder

Température de stockage

−20°C

Chaîne SMILES 

N.OCC(O)C1OC(O)(CC(O)C1O)C(O)=O

InChI

1S/C8H14O8.H3N/c9-2-4(11)6-5(12)3(10)1-8(15,16-6)7(13)14;/h3-6,9-12,15H,1-2H2,(H,13,14);1H3

Clé InChI

UDJBBKGYARWWNJ-UHFFFAOYSA-N

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Application

  • Synthesis of KDO Analogues: A significant study focused on the synthesis of analogues of 3-deoxy-D-manno-octulosonic acid (KDO), which includes compounds such as 2-Keto-3-deoxyoctonate ammonium salt. These analogues were evaluated as potential inhibitors of CMP-KDO synthetase, playing a critical role in the development of new therapeutic agents targeting bacterial infections and enhancing understanding of bacterial lipopolysaccharide synthesis (Luthman et al., 1987).

Actions biochimiques/physiologiques

KDO is a sialic acid that is a component of bacterial lipopolysaccharides and a possible target for antibiotic development.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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