900917

N-Azidoacetylmannosamine-tetraacylated

95%

• Synonyme(s) : Ac₄ManNAz
• Formule empirique (notation de Hill): C₁₆H₂₂N₄O₁₀
• Numéro CAS: 361154-30-5
• Poids moléculaire : 430.37
• Code UNSPSC : 12352116
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Pureté: 95%
• Forme: powder or crystals
• Capacité de réaction: reaction type: click chemistry
• Température de stockage: −20°C

Description

Application

N-Azidoacetylmannosamine-tetraacylated (Ac₄ManNAz) is an azide-containing metabolic glycoprotein labeling reagent that can be incorporated into the sialic acid biosynthesis pathway. The azide-modified protein can be detected by reaction with alkynes. For example alkynes labeled with a fluorescent probe or a biotin can be used. The acetyl groups increase cell permeability and allow the unnatural sugars to easily pass through the cell membrane. Carboxyesterases remove the acetyl groups once the monosaccharide is in the cell.

Tetraacylated N-azidoacetylmannosamine is generally used in click chemistry applications in bioconjugate chemistry.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable