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712469

Sigma-Aldrich

Methoxypolyethylene glycol maleimide

PEG average Mn 10,000 g/mol

Synonyme(s) :

Polyethylene glycol, MeO-PEG-Mal, PEG-maleimide, mono-Methyl polyethylene glycol 2-maleimidoethyl ether

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About This Item

Numéro CAS:
99126-64-4
Numéro MDL:
MFCD00803681
Code UNSPSC :
12352111
Nomenclature NACRES :
NA.22

Forme

powder

Poids mol.

PEG average Mn 10,000 g/mol

Extrémité Ω

maleimide

Extrémité α

methoxy

Température de stockage

−20°C

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Application

  • Thiol-disulfide redox proteomics in plant research.: This paper discusses the application of thiol-disulfide redox proteomics in plant research, emphasizing the role of redox modifications in protein functions. The use of Methoxypolyethylene glycol maleimide as a PEGylation reagent for bioconjugation in these studies highlights its significance in protein modification and drug delivery systems, providing insights into redox-dependent regulation mechanisms in plants (Muthuramalingam et al., 2010).

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Jixiao Niu et al.
Nature, 573(7772), 139-143 (2019-08-30)
Signal transducer and activator of transcription 3 (STAT3) has a critical role in regulating cell fate, inflammation and immunity1,2. Cytokines and growth factors activate STAT3 through kinase-mediated tyrosine phosphorylation and dimerization3,4. It remains unknown whether other factors promote STAT3 activation through

Articles

Polyethylene Glycol Building Blocks for PEGylation

Circulatory half-life is a key success factor for new drugs. In this respect, PEGylation or PEG-ing—the modification of potential candidates ranging from non-peptidic small molecules to peptides and proteins, antibody fragments, aptamers, and saccharides or oligonucleotides with polyethylene glycol chains—offers numerous advantages.

Polyethylene Glycol Building Blocks for PEGylation

Circulatory half-life is a key success factor for new drugs. In this respect, PEGylation or PEG-ing—the modification of potential candidates ranging from non-peptidic small molecules to peptides and proteins, antibody fragments, aptamers, and saccharides or oligonucleotides with polyethylene glycol chains—offers numerous advantages.

Polyethylene Glycol Building Blocks for PEGylation

Circulatory half-life is a key success factor for new drugs. In this respect, PEGylation or PEG-ing—the modification of potential candidates ranging from non-peptidic small molecules to peptides and proteins, antibody fragments, aptamers, and saccharides or oligonucleotides with polyethylene glycol chains—offers numerous advantages.

Polyethylene Glycol Building Blocks for PEGylation

Circulatory half-life is a key success factor for new drugs. In this respect, PEGylation or PEG-ing—the modification of potential candidates ranging from non-peptidic small molecules to peptides and proteins, antibody fragments, aptamers, and saccharides or oligonucleotides with polyethylene glycol chains—offers numerous advantages.

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