538795

2-Trifluoromethyl-2-propanol

96%

• Formule linéaire : CF₃C(CH₃)₂OH
• Numéro CAS: 507-52-8
• Poids moléculaire : 128.09
• Numéro CE : 208-075-3
• Numéro MDL: MFCD00014391
• Code UNSPSC : 12352100
• ID de substance PubChem : 24878360
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: 96%
• Indice de réfraction: n20/D 1.3335 (lit.)
• Point d'ébullition: 83 °C (lit.)
• Densité: 1.17 g/mL at 25 °C (lit.)
• Chaîne SMILES: CC(C)(O)C(F)(F)F
• InChI: 1S/C4H7F3O/c1-3(2,8)4(5,6)7/h8H,1-2H3
• Clé InChI: OCGWWLDZAFOHGD-UHFFFAOYSA-N

Description

Description générale

2-Trifluoromethyl-2-propanol is a fluorinated aliphatic alcohol. It can be prepared by reacting methyllithium, trifluoroacetone and trifluorovinyl bromide in ether. This can also be synthesized from the reaction between methylmagnesium bromide and 1,1,1-trifluoroacetone in ether.

Application

2-Trifluoromethyl-2-propanol may be employed as a solvent for the preparation of [¹⁸F]fluorothymidine. It may also be used in the synthesis of [2-(trifluoromethyl)-2-propyl nitrate] through nitration in nitric acid/trifluoroacetic anhydride.

Informations sur la sécurité

• Pictogrammes: GHS02
• Mention d'avertissement: Danger
• Mentions de danger: H225
• Conseils de prudence: P210
• Classification des risques: Flam. Liq. 2
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 59.0 °F - closed cup
• Point d'éclair (°C): 15 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter