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190047

Sigma-Aldrich

(−)-p-Bromolevamisole oxalate

99%

Synonyme(s) :

(−)-4-Bromotetramisole oxalate, 6-Bromolevamisole oxalate, S(−)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate

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About This Item

Formule empirique (notation de Hill):
C11H11BrN2S · C2H2O4
Numéro CAS:
62284-79-1
Poids moléculaire :
373.22
Numéro Beilstein :
4944883
Numéro CE :
263-487-0
Numéro MDL:
MFCD00070406
Code UNSPSC :
12352200
ID de substance PubChem :
24278147
Nomenclature NACRES :
NA.06

Pureté

99%

Forme

powder

Activité optique

[α]25/D −104°, c = 0.5 in H2O

Pf

192 °C (dec.) (lit.)

Chaîne SMILES 

OC(=O)C(O)=O.Brc1ccc(cc1)[C@H]2CN3CCSC3=N2

InChI

1S/C11H11BrN2S.C2H2O4/c12-9-3-1-8(2-4-9)10-7-14-5-6-15-11(14)13-10;3-1(4)2(5)6/h1-4,10H,5-7H2;(H,3,4)(H,5,6)/t10-;/m1./s1

Clé InChI

ZULBIBHDIQCNIS-HNCPQSOCSA-N

Catégories apparentées

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302 + H312

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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T Metaye et al.
Biochemical pharmacology, 37(22), 4263-4268 (1988-11-15)
Analogues of bromo-levamisole and guanidine derivatives including cimetidine are examined in vitro in order to investigate their comparative inhibition, towards alkaline phosphatase (ALP) from human liver and diamine-oxidase (DAO) from human placenta. Bromo-levamisole, considered as a potent selective uncompetitive inhibitor
R Béliveau et al.
The International journal of biochemistry, 20(4), 375-380 (1988-01-01)
1. Brush border membranes purified from rat kidney cortex were incubated in the presence of ATP and analysed by SDS polyacrylamide gel electrophoresis. 2. Quantitative analysis of phosphorylation was performed with a calibration curve obtained by autoradiography. 3. The presence
D G Williams et al.
Enzyme, 33(2), 70-74 (1985-01-01)
The dye Reactive Yellow 13, an affinity reagent for intestinal alkaline phosphatase, inhibits intestinal and other human alkaline phosphatases in solution. The inhibition depends markedly on the presence of a phosphate acceptor such as diethanolamine. The dye is an uncompetitive
J H Wöltgens et al.
Journal de biologie buccale, 13(1), 3-10 (1985-03-01)
This study was designed to compare the various phosphatases and pyrophosphatases in bone with those in developing teeth. Moreover the alkaline phosphatase inhibitor 1-p-bromotetramisole (1-pBTM) was assessed for its ability to discriminate between the several phosphatase activities. Enzyme activities were
S N Smith et al.
The American journal of physiology, 274(2 Pt 1), C492-C499 (1998-03-05)
Some cystic fibrosis transmembrane conductance regulator (CFTR) mutations, such as G551D, result in a correctly localized Cl- channel at the cell apical membrane, albeit with markedly reduced function. Patch-clamp studies have indicated that both phosphatase inhibitors and 3-isobutyl-1-methylxanthine (IBMX) can
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