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860538P

Avanti

C8 Galactosyl(β) Ceramide (d18:1/8:0)

Avanti Research™ - A Croda Brand 860538P, powder

Synonym(s):

D-galactosyl-β-1,1′ N-octanoyl-D-erythro-sphingosine

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About This Item

Empirical Formula (Hill Notation):
C32H61NO8
CAS Number:
41613-16-5
Molecular Weight:
587.83
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 25 mg (860538P-25mg)
pkg of 1 × 5 mg (860538P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860538P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O

InChI

1S/C32H61NO8/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-26(35)25(33-28(36)22-20-17-8-6-4-2)24-40-32-31(39)30(38)29(37)27(23-34)41-32/h19,21,25-27,29-32,34-35,37-39H,3-18,20,22-24H2,1-2H3,(H,33,36)/b21-19+/t25-,26+,27?,29-,30?,31?,32+/m0/s1

InChI key

LCEXEEHGNKGJES-JLZVVTAUSA-N

General description

Galactosyl ceramide is a complex glycosphingolipid, which is a major component of the myelin sheath. It consists of a single galactose residue linked to ceramide.

Application

C8 Galactosyl(β) Ceramide (d18:1/8:0) may be suitable for the preparation of liposomes.

Biochem/physiol Actions

Galactosyl ceramide is necessary for normal myelin function and stability.

Packaging

5 mL Amber Glass Screw Cap Vial (860538P-25mg)
5 mL Amber Glass Screw Cap Vial (860538P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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C8-glycosphingolipids preferentially insert into tumor cell membranes and promote chemotherapeutic drug uptake
Pedrosa L, et al.
Biochimica et Biophysica Acta - Biomembranes, 1848(8), 1656-1670 (2015)
Gangliosides in Health and Disease (2018)
Pediatric Neurology (2013)
Divalent cation-mediated interaction between cerebroside sulfate and cerebrosides: an investigation of the effect of structural variations of lipids by electrospray ionization mass spectrometry
Koshy KM, et al.
Biophysical Journal, 77(1), 306-318 (1999)
Biyu Hou et al.
Life sciences, 245, 117352-117352 (2020-02-02)
The depot-specific differences in lipidome of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) reflect heterogeneity of white adipose tissue (WAT), which plays a central role in its distinct response to outside stimuli. However, the detailed lipidome of depot-specific
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