Organocatalytic asymmetric direct alkylation of alpha-diazoester via C-H bond cleavage.

Organocatalytic asymmetric direct alkylation of alpha-diazoester via C-H bond cleavage.

Journal of the American Chemical Society (2005-06-30)

Daisuke Uraguchi, Keiichi Sorimachi, Masahiro Terada

RÉSUMÉ

A new variant of phosphoric acid-catalyzed C-C bond forming reaction, direct alkylation of alpha-diazoester, via C-H bond cleavage is presented. The resulting products, beta-amino-alpha-diazoesters, are highly functionalized and useful synthetic precursors for various types of beta-amino acids.

MATÉRIAUX

Référence du produit

Marque

Description du produit

695718

Sigma-Aldrich

(R)-3,3′-Bis(9-anthracenyl)-1,1′-binaphthyl-2,2′-diyl hydrogenphosphate, 95%