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  • A comparison of botulinum toxin a and intralesional steroids for the treatment of plantar fasciitis: a randomized, double-blinded study.

A comparison of botulinum toxin a and intralesional steroids for the treatment of plantar fasciitis: a randomized, double-blinded study.

Foot & ankle international (2013-02-07)
Jorge Elizondo-Rodriguez, Yariel Araujo-Lopez, J Alberto Moreno-Gonzalez, Eloy Cardenas-Estrada, Oscar Mendoza-Lemus, Carlos Acosta-Olivo
RÉSUMÉ

The objective of this study was to compare intramuscularly applied botulinum toxin A (BTX-A) in the gastroc-soleus complex with intralesional steroids for the treatment of plantar fasciitis. The patients were randomly divided into 2 groups according to the treatment received. The patients were evaluated over 6 months. The evaluation scores included the Visual Analog Scale (VAS), Maryland Foot and Ankle, Foot and Ankle Disability Index (FADI), and American Orthopaedic Foot and Ankle Society (AOFAS) score. Moreover, patients were instructed to perform plantar fascia stretching exercises over the course of the study. The final number of patients was 36, of whom 19 received BTX-A (10 men and 9 women) and 17 (6 men and 11 women) received steroids. When compared to patients who received steroids, the patients who received BTX-A exhibited more rapid and sustained improvement over the duration of the study. A combination of BTX-A and plantar fascia stretching exercises yielded better results for the treatment of plantar fasciitis than intralesional steroids. Level I, therapeutic studies.

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Dexamethasone isonicotinate for impurity C identification, European Pharmacopoeia (EP) Reference Standard
Dexamethasone isonicotinate, European Pharmacopoeia (EP) Reference Standard