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Superparamagnetic nanoparticle-supported enzymatic resolution of racemic carboxylates.

Chemical communications (Cambridge, England) (2005-09-02)
Hari M R Gardimalla, Deendayal Mandal, Philip D Stevens, Max Yen, Yong Gao
RÉSUMÉ

Candida rugosa lipase immobilized on maghemite nanoparticles demonstrated high stereoselectivity in kinetic resolution of racemic carboxylates and improved long-term stability over its parent free enzyme, allowing the supported enzyme to be repeatedly used for a series of chiral resolution reactions.

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Sigma-Aldrich
Acide (±)-2-bromopropionique, 99%