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  • Stereoselective synthesis of myo-inositol via ring-closing metathesis: a building block for glycosylphosphatidylinositol (GPI) anchor synthesis.

Stereoselective synthesis of myo-inositol via ring-closing metathesis: a building block for glycosylphosphatidylinositol (GPI) anchor synthesis.

Organic letters (2002-04-13)
Rosemary M Conrad, Michael J Grogan, Carolyn R Bertozzi
RÉSUMÉ

Here we report a concise stereoselective synthesis of myo-inositol via ring-closing metathesis. A readily available bis-Weinreb amide of D-tartrate served as a key intermediate. [reaction: see text]

MATÉRIAUX
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Description du produit

Sigma-Aldrich
(+)-Dimethyl 2,3-O-isopropylidene-D-tartrate, 98%