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1370600

USP

Lovastatin

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

Mevinolin

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About This Item

Formule empirique (notation de Hill):
C24H36O5
Numéro CAS:
75330-75-5
Poids moléculaire :
404.54
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

lovastatin

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

InChI

1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1

Clé InChI

PCZOHLXUXFIOCF-BXMDZJJMSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lovastatin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Lovastatin Tablets
  • Simvastatin
  • Simvastatin Tablets

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1370611

Lovastatin Related Compound A, United States Pharmacopeia (USP) Reference Standard

L0790000

Lovastatin, European Pharmacopoeia (EP) Reference Standard

Y0001136

Lovastatin for peak identification, European Pharmacopoeia (EP) Reference Standard

1370655

Lovastatin Impurity Identification Mixture, United States Pharmacopeia (USP) Reference Standard

1236833

Lovastatin Epimer Mixture, United States Pharmacopeia (USP) Reference Standard

1443216

Mevastatin, United States Pharmacopeia (USP) Reference Standard

PHR2240

Mevastatin/Lovastatin Impurity A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2278

Lovastatin Impurity C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2279

Lovastatin Impurity D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2277

Lovastatin Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Warning

Mentions de danger

H351,H361f

Classification des risques

Carc. 2 - Repr. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Enrico Peiretti et al.
Experimental eye research, 124, 11-16 (2014-05-06)
Starting from previous studies showing that patients with cognitive deficit present neutral lipids (NLs) accumulation in cytoplasm of their peripheral blood mononuclear cells (PBMCs) and considering that there is epidemiological evidence linking age-related macular degeneration (AMD) to cognitive deficit, the
Takashi Ohkura et al.
Journal of virology, 88(17), 10039-10055 (2014-06-27)
In polarized epithelial cells, influenza A virus hemagglutinin (HA) and neuraminidase (NA) are intrinsically associated with lipid rafts and target the apical plasma membrane for viral assembly and budding. Previous studies have indicated that the transmembrane domain (TMD) and cytoplasmic
Dae-Hyoung Yoo et al.
Drug metabolism and disposition: the biological fate of chemicals, 42(9), 1508-1513 (2014-06-21)
Orally administered drugs may be metabolized by intestinal microbial enzymes before absorption into the blood. Accordingly, coadministration of drugs affecting the metabolic activities of gut microbes (e.g., antibiotics) may lead to drug-drug interactions (DDI). In this study, gut microbiota-mediated DDI
Giovanni Provenzano et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(40), 13281-13288 (2014-10-03)
Genome-wide association studies indicated the homeobox-containing transcription factor Engrailed-2 (En2) as a candidate gene for autism spectrum disorders (ASD). Accordingly, En2 knock-out (En2(-/-)) mice show anatomical and behavioral "ASD-like" features, including decreased sociability and learning deficits. The molecular pathways underlying
Chantel D Campbell et al.
Biopolymers, 93(9), 755-763 (2010-06-26)
The fungal polyketide lovastatin is a cholesterol lowering agent that is an immediate precursor to a multi-billion dollar drug, simvastatin (Zocor). Lovastatin is produced by an iterative type I polyketide synthase known as LovB and a partner enoyl reductase (LovC).
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