SBR00068
Streptomycin Ready Made Solution
100 mg/mL in water
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About This Item
Produits recommandés
Forme
liquid
Niveau de qualité
Activité spécifique
(Antibacterial)
Concentration
100 mg/mL in water
Spectre d'activité de l'antibiotique
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
Mode d’action
protein synthesis | interferes
Température de stockage
−20°C
Description générale
Chemical structure: aminoglycoside
Application
Streptomycin is used to study mechanisms of streptomycin resistance and is often used together with penicillin and other agents to inhibit bacterial contamination in cell culture applications. It is recommended for use in molecular biology applications at 25-50 μg/mL, in cell culture applications at 100 mg/L and in embryo culture at 50 mg/L.
Actions biochimiques/physiologiques
Mode of Action: Streptomycin acts by inhibiting prokaryote protein synthesis by binding to the S12 protein of the 30S ribosomal subunit, thus preventing the transition from imitation complex to chain-elongating ribosome. This causes miscoding or inhibits initiation.
Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.
Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.
Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.
Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.
Stockage et stabilité
- Streptomycin ready made solution contains 100 mg/mL streptomycin sulfate in water.
- Streptomycin: sulfate salt ratio is 1:1.5.
- The product is packed under aseptic conditions.
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Repr. 2
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 3
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