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Key Documents

I1774

Sigma-Aldrich

Iturin A from Bacillus subtilis

≥95% (HPLC), suitable for microbiological culture

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About This Item

Numéro CAS:
52229-90-0
Numéro MDL:
MFCD01094135
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.61

product name

Iturin A from Bacillus subtilis, ≥95% (HPLC)

Source biologique

Bacillus subtilis

Niveau de qualité

200

Pureté

≥95% (HPLC)

Forme

powder

Technique(s)

microbiological culture: suitable

Couleur

white to yellow

Solubilité

ethanol: soluble 9.80-10.20 mg/mL

Spectre d'activité de l'antibiotique

fungi

Mode d’action

cell membrane | interferes

Température de stockage

2-8°C

Application

Iturin A was used in the study of Bacillomycin D (an iturin with antifungal activity against Aspergillus flavus).

Actions biochimiques/physiologiques

IturinA exhibits strong antifungal activity against pathogenic yeast and fungi. It interacts with the cytoplasmic membrane of the target cell forming ion conducting pores. Its mode of action could be attributed to its interaction with sterols and phospholipids. The compound causes the release of exo-vesicles from human erythrocytes.

Autres remarques

A family of lipopeptides characterized by a heptapeptide cyclized with a C13-C17 β-amino fatty acid. Composed mainly of C14-C15 β-amino acids.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Chie Niisawa et al.
The Journal of general and applied microbiology, 54(3), 149-158 (2008-07-26)
A composting product of marine animal resources has been used as a fertilizer and a soil conditioner in Japan. This compost was produced by a repeated fed-batch fermentation system with three successive aerobic bioreactors. Composting temperature reached about 75 degrees
E Jourdan et al.
Molecular plant-microbe interactions : MPMI, 22(4), 456-468 (2009-03-11)
Multiple strains of Bacillus subtilis were demonstrated to stimulate plant defense responses, and cyclic lipopeptides may be involved in the elicitation of this induced systemic resistance phenomenon. Here, we further investigated molecular events underlying the interaction between such lipopeptides and
S Mizumoto et al.
Applied microbiology and biotechnology, 75(6), 1267-1274 (2007-04-25)
Enhanced production of the antibiotic iturin A by Bacillus subtilis RB14-CS reached 4.4 g L(-1) in SM medium containing soybean meal and maltose, which was 16-fold and 2.2-fold higher than that in original and modified number 3S media, respectively. When
Katarzyna Czaczyk et al.
Polish journal of microbiology, 57(4), 313-319 (2008-01-01)
Cell surface hydrophobicity (CSH) is recognised as a important factor in microbial adhesion to solid surfaces. Growth conditions have been found to determine the synthesis of extracellular molecules by microorganisms. It has major consequences in modification of bacterial surface properties
Jun Yuan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(26), 2746-2750 (2011-08-30)
Iturin A, a powerful antifungal surfactant, is a kind of bacterial lipopeptide produced by Bacillus strains. This study addresses the use of an aqueous two-phase system (ATPS) using ethanol/ammonium sulfate to extract iturin A from Bacillus amyloliquefaciens NJN-6 fermentation broth
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