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G3002

Sigma-Aldrich

Gly-Pro

≥98%, suitable for ligand binding assays

Synonyme(s) :

glycyl-L-proline

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About This Item

Formule empirique (notation de Hill):
C7H12N2O3
Numéro CAS:
704-15-4
Poids moléculaire :
172.18
Numéro CE :
211-880-2
Code UNSPSC :
12352202
ID de substance PubChem :
24895111
Nomenclature NACRES :
NA.26

product name

Gly-Pro,

Pureté

≥98%

Niveau de qualité

200

Forme

solid

Technique(s)

ligand binding assay: suitable

Couleur

white

Température de stockage

−20°C

Chaîne SMILES 

NCC(N1[C@H](C(O)=O)CCC1)=O

InChI

1S/C7H12N2O3/c8-4-6(10)9-3-1-2-5(9)7(11)12/h5H,1-4,8H2,(H,11,12)

Clé InChI

KZNQNBZMBZJQJO-UHFFFAOYSA-N

Application


  • Diagnostic efficacy of [(68)Ga]Ga-DOTA-GPFAPI-04 in patients with solid tumors in a head-to-head comparison with [(18)F]F-FDG: results from a prospective clinical study.: This study explores the use of Gly-Pro in peptide imaging agents, specifically [(68)Ga]Ga-DOTA-GPFAPI-04, demonstrating its superior diagnostic performance in detecting solid tumors compared to traditional imaging modalities, offering new avenues for cancer diagnosis and monitoring (Yuan et al., 2024).

  • Understanding the Transepithelial Transport and Transbilayer Diffusion of the Antihypertensive Peptide Asn-Cys-Trp: Insights from Caco-2 Cell Monolayers and the DPPC Model Membrane.: This research demonstrates the utility of Gly-Pro in studying the absorption and metabolic stability of antihypertensive peptides, providing key insights into their pharmacokinetic behaviors and enhancing drug delivery strategies (Wu et al., 2024).

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H319

Conseils de prudence

P305 + P351 + P338

Classification des risques

Eye Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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E Berardesca et al.
The British journal of dermatology, 126(2), 193-195 (1992-02-01)
A case is reported of a 15-year-old boy with prolidase deficiency and marked urinary excretion of the iminodipeptide gly-pro. Prolidase activity of erythrocytes against substrate glycyl-proline was deficient, but after blood transfusions this was increased to 15.7% of donor activity
Poonam Kalhotra et al.
Biomolecules, 10(2) (2020-02-23)
Diabetes mellitus is a severe health problem in Mexico, and its prevalence is increasing exponentially every year. Recently, DPP-4 (dipeptidyl peptidase-4) inhibitors have become attractive oral anti-hyperglycemic agents to reduce the pathology of diabetes. Gliptin's family, such as sitagliptin, vildagliptin
Mitsuru Tanaka et al.
Scientific reports, 9(1), 5769-5769 (2019-04-10)
Apart from nutrients required for the brain, there has been no report that naturally occurring peptides can cross the blood-brain barrier (BBB). The aim of this study was to identify the BBB-transportable peptides using in situ mouse perfusion experiments. Based
C Méthivier et al.
Faraday discussions, 204, 69-81 (2017-08-03)
Adsorption of the Glycine-Proline (Gly-Pro) dipeptide has been investigated using surface science complementary techniques on Au(110) and Ag(110), showing some interesting differences both in the chemical form and surface organization of the adsorbed peptide. On Au(110), Gly-Pro mainly adsorbs in
Rong Qiu et al.
Scientific reports, 10(1), 8231-8231 (2020-05-20)
In this study, we used a new coating agent, that is, ultra-purified alginate gel (UPAL), for fetal liver tissue transplantation. This study aims to compare the effect of UPAL with the effect of other coating agents on improving the effect
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