D1377

2,6-Diaminopimelic acid

≥98% (TLC), suitable for thin layer chromatography (TLC)

• Synonyme(s) : 2,6-Diaminoheptanedioic acid
• Formule linéaire : HOOCCH(NH₂)(CH₂)₃CH(NH₂)COOH
• Numéro CAS: 583-93-7
• Poids moléculaire : 190.20
• Numéro Beilstein : 1787719
• Numéro CE : 209-524-6
• Numéro MDL: MFCD00002637
• Code UNSPSC : 12352209
• ID de substance PubChem : 24893417
• Nomenclature NACRES : NA.26

Propriétés

• product name: 2,6-Diaminopimelic acid, ≥98% (TLC)
• Pureté: ≥98% (TLC)
• Forme: powder
• Technique(s): thin layer chromatography (TLC): suitable
• Couleur: white to off-white
• Pf: ~295 °C (dec.) (lit.)
• Application(s): peptide synthesis
• Chaîne SMILES: NC(CCCC(N)C(O)=O)C(O)=O
• InChI: 1S/C7H14N2O4/c8-4(6(10)11)2-1-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)
• Clé InChI: GMKMEZVLHJARHF-UHFFFAOYSA-N

Description

Description générale

2,6-Diaminopimelic acid is produced in bacteria and is a component of cell wall. It is also synthesized by higher plants.

Application

2,6-Diaminopimelic acid (DAP) has been used:

• as a supplement in glucose minimal media for screening Bacillus subtilis(44)
• as a component of lysogeny broth (LB) agar for screening E coli transformants(45)
• as a standard in thin layer chromatography for the characterization of DAP isoforms from Streptomyces strains(46)

Actions biochimiques/physiologiques

2,6-Diaminopimelic acid is essential for microbial metabolism and is a potential marker for quantification of microbial proteins. It is a sensitive and reliable marker and is majorly quantified using gradient high-performance liquid chromatography (HPLC).

Autres remarques

Mixture of LL-, DD- and meso-isomers.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves