A7469

L-Alanine

98.5-101.0%, suitable for cell culture, BioXtra, non-animal source

• Synonyme(s) : (S)-2-Aminopropionic acid, L-α-Aminopropionic acid
• Formule empirique (notation de Hill): C₃H₇NO₂
• Numéro CAS: 56-41-7
• Poids moléculaire : 89.09
• Numéro Beilstein : 1720248
• Numéro CE : 200-273-8
• Numéro MDL: MFCD00064410
• Code UNSPSC : 12352209
• eCl@ss : 32160406
• ID de substance PubChem : 24891241
• Nomenclature NACRES : NA.26

Propriétés

• product name: L-Alanine, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%
• Source biologique: non-animal source
• Niveau de qualité: 200
• Agence: meets EP testing specifications; meets USP testing specifications
• Gamme de produits: BioXtra
• Pureté: 98.5-101.0%
• Forme: powder
• Technique(s): cell culture | mammalian: suitable
• Impuretés: endotoxin, tested
• Couleur: white
• Solubilité: H₂O: 100 mg/mL
• Application(s): peptide synthesis; pharmaceutical (small molecule)
• Chaîne SMILES: C[C@H](N)C(O)=O
• InChI: 1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1
• Clé InChI: QNAYBMKLOCPYGJ-REOHCLBHSA-N
• Informations sur le gène: human ... CA1(759) , CA2(760)

Description

Application

L-Alanine has been used for tissue culture technique as a media component. It has been used as a media component for the growth of adult mouse keratinocytes.

Actions biochimiques/physiologiques

L-Alanine is a nonessential amino acid, which is highly concentrated in muscle. It is a key player in the Glucose-Alanine cycle, which enables the removal of pyruvate and glutamate from muscle to the liver. Once in the liver, glucose is regenerated from pyruvate and returned to the muscle while glutamate ultimately participates in the urea cycle to form urea. The Glucose-Alanine cycle aides to conserve ATP in muscle for muscle contraction, while the energy burden of gluconeogenesis is imposed upon the liver. Alanine inhibits pyruvate kinase to regulate gluconeogenesis and glycolysis in order to maintain glucose homeostasis during starvation. Alanine prevents hepatic autophagy. Alanine formation is a result of transamination of glutamate and pyruvate.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)