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Key Documents

Y0001256

Levetiracetam impurity C

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

2-Hydroxypyridine, 2(1H)-Pyridone, 2-Pyridinol

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About This Item

Formule empirique (notation de Hill):
C5H5NO
Numéro CAS:
Poids moléculaire :
95.10
Numéro Beilstein :
105757
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

levetiracetam

Fabricant/nom de marque

EDQM

Point d'ébullition

280-281 °C (lit.)

Pf

105-107 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

Oc1ccccn1

InChI

1S/C5H5NO/c7-5-3-1-2-4-6-5/h1-4H,(H,6,7)

Clé InChI

UBQKCCHYAOITMY-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Levetiracetam impurity C EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

Skull and crossbones

Mention d'avertissement

Danger

Mentions de danger

Conseils de prudence

Classification des risques

Acute Tox. 3 Oral

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Certificats d'analyse (COA)

Lot/Batch Number

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Christian Wiegand et al.
Chemical communications (Cambridge, England), 48(82), 10195-10197 (2012-09-11)
3-Substituted 2-pyridones were enantioselectively (68-90% ee) converted into the respective 3-hydroxypyridine-2,6-diones by a sequence consisting of a template-mediated type II photooxygenation and an acid-catalysed rearrangement.
Mingwen Zhu et al.
Chemical communications (Cambridge, England), 47(48), 12876-12878 (2011-11-15)
A highly efficient and convenient CuCl/2-pyridonate catalytic system for oxidative homocoupling of azoles affording a biazole product has been developed. With this system, a variety of biazoles have been effectively synthesized in good to excellent yields in the presence of
Ken-ichi Kusakabe et al.
Bioorganic & medicinal chemistry, 21(7), 2045-2055 (2013-02-12)
Selective CB2 agonists have the potential for treating pain without central CB1-mediated adverse effects. Screening efforts identified 1,2-dihydro-3-isoquinolone 1; however, this compound has the drawbacks of being difficult to synthesize with two asymmetric carbons on an isoquinolone scaffold and of
Istvan Horvath et al.
Archives of biochemistry and biophysics, 532(2), 84-90 (2013-02-13)
In a recent study we discovered that a ring-fused 2-pyridone compound triggered fibrillization of a key protein in Parkinson's disease, α-synuclein. To reveal how variations in compound structure affect protein aggregation, we now prepared a number of strategic analogs and
Mettu Ravinder et al.
Bioorganic & medicinal chemistry letters, 22(18), 6010-6015 (2012-08-18)
Twenty-six 2-pyridone derivatives (8a-8z), which are structurally analogous to amrinone and milrinone two important cardiotonic drugs, are synthesized and characterized. The synthesis of 2-pyridone derivatives involves addition, followed by cyclization between Baylis-Hillman acetates (7a-7k) and enamino esters or nitriles (3a-3e).

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