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Y0000027

Succinate de sumatriptan

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

GR-43175, Succinate de 3-[2-(diméthylamino)éthyl]- N-méthyl-1H-indole-5-méthanesulfonamide

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About This Item

Formule empirique (notation de Hill):
C14H21N3O2S · C4H6O4
Numéro CAS:
103628-48-4
Poids moléculaire :
413.49
Numéro MDL:
MFCD00902856
Code UNSPSC :
41116107
ID de substance PubChem :
329830819
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

sumatriptan

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

−20°C

Chaîne SMILES 

OC(=O)CCC(O)=O.CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1

InChI

1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3;1-2H2,(H,5,6)(H,7,8)

Clé InChI

PORMUFZNYQJOEI-UHFFFAOYSA-N

Informations sur le gène

human ... HTR1B(3351) , HTR1D(3352)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sumatriptan for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Le succinate de sumatriptan est un agoniste des récepteurs de la sérotonine 5-HT1.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1642201

Succinate de sumatriptan, United States Pharmacopeia (USP) Reference Standard

1642212

Sumatriptan Succinate Related Compound A, United States Pharmacopeia (USP) Reference Standard

Y0000026

Sumatriptan impurity mixture, European Pharmacopoeia (EP) Reference Standard

Y0000022

Succinate de sumatriptan, European Pharmacopoeia (EP) Reference Standard

1642154

Sumatriptan, United States Pharmacopeia (USP) Reference Standard

1642256

Sumatriptan succinate Related Impurities, United States Pharmacopeia (USP) Reference Standard

1642223

Composé C apparenté au succinate de sumatriptan, United States Pharmacopeia (USP) Reference Standard

BP950

Succinate de sumatriptan, British Pharmacopoeia (BP) Reference Standard

PHR2579

Sumatriptan, pharmaceutical secondary standard, certified reference material

PHR2914

Sumatriptan Succinate Related Compound C, certified reference material, pharmaceutical secondary standard

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Warning

Mentions de danger

H361d,H412

Classification des risques

Aquatic Chronic 3 - Repr. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Toshihiko Tomita et al.
Journal of gastroenterology and hepatology, 28(1), 106-111 (2012-09-20)
Scintigraphy is a useful noninvasive technique for assessment of gastric motility, especially emptying, but there is little knowledge of use of the technique to assess gastric accommodation. Therefore, to clarify the usefulness of scintigraphy as a technique for assessing gastric
Benjamin W Friedman et al.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 19(10), 1151-1157 (2012-09-22)
Patients who use an emergency department (ED) for acute migraine headaches have higher migraine disability scores, lower socioeconomic status, and are unlikely to have used a migraine-specific medication prior to presentation to the ED. The objective was to determine if
Christian Asseburg et al.
International journal of technology assessment in health care, 28(4), 382-389 (2012-09-28)
The cost-effectiveness of triptans in the treatment of migraine has not been assessed since generic sumatriptan entered the Finnish market in 2008. Using systematic review and mixed treatment comparison, the effectiveness of triptans was estimated with regard to 2-hour response
Daxesh P Patel et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 902, 122-131 (2012-07-24)
An ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method has been developed for the simultaneous determination of sumatriptan and naproxen in human plasma using naratriptan and indomethacin as the internal standards (ISs). The plasma samples were prepared by solid phase
M J Cózar-Bernal et al.
Journal of pharmaceutical and biomedical analysis, 72, 251-260 (2012-10-16)
In this paper, a novel, precise, specific, accurate and rapid reversed-phase high performance liquid chromatographic method was developed, optimized and validated for determining sumatriptan succinate in niosomes with the best chromatographic peak resolution, reduced run time and low cost of
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