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933856

Sigma-Aldrich

γ-Valerolactone

greener alternative

BioRenewable, anhydrous, DMF and NMP substitute, ≥99%

Synonyme(s) :

4,5-Dihydro-5-methyl-2(3H)-furanone, GVL, γ-Methyl-γ-butyrolactone, 4,5-Dihydro-5-methyl-2(3H)-furanone, 4-Hydroxypentanoic acid lactone

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About This Item

Formule empirique (notation de Hill):
C5H8O2
Numéro CAS:
Poids moléculaire :
100.12
Numéro Beilstein :
80420
Numéro MDL:
Code UNSPSC :
12352100
Nomenclature NACRES :
NA.21

Densité de vapeur

3.45 (vs air)

Niveau de qualité

Pureté

≥99%

Forme

liquid

Caractéristiques du produit alternatif plus écologique

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Impuretés

≤50 ppm water

Couleur

colorless to light yellow

Indice de réfraction

n20/D 1.432 (lit.)

Point d'ébullition

207-208 °C (lit.)
82-85 °C/10 mmHg (lit.)

Pf

−31 °C (lit.)

Densité

1.05 g/mL at 25 °C (lit.)

Autre catégorie plus écologique

Chaîne SMILES 

CC1CCC(=O)O1

InChI

1S/C5H8O2/c1-4-2-3-5(6)7-4/h4H,2-3H2,1H3

Clé InChI

GAEKPEKOJKCEMS-UHFFFAOYSA-N

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Description générale

We are committed to providing environmentally friendly products, and γ-Valerolactone (GVL) is a prime example of our dedication to this effort. GVL is a bio-based solvent derived from renewable sources, which makes it a sustainable alternative to traditional organic solvents like NMP and DMF. GVL aligns with the principles of "Use of Renewable Feedstocks" and "Safer Solvents and Auxiliaries" and offers exceptional solubility properties. As a result, it is an effective solvent for various applications, such as chemical synthesis. GVL is non-toxic, non-irritating, and biodegradable, making it a safe and eco-friendly choice for both consumers and the environment. Overall, γ-Valerolactone is an excellent option for companies and researchers seeking to reduce their environmental footprint while still delivering high-quality products.

Application

  • Peptide synthesis
  • Cross-coupling reactions
  • Nonaqueous redox-flow batteries
  • Polymerization reaction
  • Extraction

Caractéristiques et avantages

  • Bio-based
  • Made from Renewable Resource - rice
  • Biodegradable
  • Non-toxic
  • Low vapor pressure

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

204.8 °F - closed cup

Point d'éclair (°C)

96 °C - closed cup


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Certificats d'analyse (COA)

Lot/Batch Number

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Green solid-phase peptide synthesis 4. γ-Valerolactone and N-formylmorpholine as green solvents for solid phase peptide synthesis
Kumar A, et al.
Tetrahedron Letters, 58, 2986-2988 (2017)
γ-Valerolactone as an alternative biomass-derived medium for the Sonogashira reaction
Green Chemistry, 17, 1071-1076 (2015)
Nonaqueous redox-flow batteries: organic solvents, supporting electrolytes, and redox pairs
Ke Gong, Qianrong Fang, Shuang Gu, Sam Fong Yau Li and Yushan Yan
Energy & Environmental Science, 8, 3515-3530 (2015)
γ-Valerolactone as a Green Solvent for Extracting Carboxylic Acids and Alcohols from n-Tetradecane: Equilibrium Data for Model Systems at 298.15 K
Carlos E. S. Dantas and Roberta Ceriani
Journal of Chemical and Engineering Data, Volume 67, Issue 6, 1460?1473-1460?1473 (2022)
Greening Fmoc/tBu solid-phase peptide synthesis
Musaimi O A, et al.
Green Chemistry, 22, 996-1018 (2020)

Contenu apparenté

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Why should you have to choose between solvents that are ecological and those that are reliable? Enjoy both at once with our biorenewable and greener solutions. Cyrene™ solvent is a new dipolar aprotic alternative to common REACH restricted solvents, such as N methyl-2-pyrrolidone (NMP) and Dimethylformamide (DMF).

Why should you have to choose between solvents that are ecological and those that are reliable? Enjoy both at once with our biorenewable and greener solutions. Cyrene™ solvent is a new dipolar aprotic alternative to common REACH restricted solvents, such as N methyl-2-pyrrolidone (NMP) and Dimethylformamide (DMF).

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