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484407

Sigma-Aldrich

1-Methoxy-2-propanol

greener alternative

≥99.5%

Synonyme(s) :

Éther méthylique de propylène glycol

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About This Item

Formule linéaire :
CH3CH(OH)CH2OCH3
Numéro CAS:
107-98-2
Poids moléculaire :
90.12
Numéro Beilstein :
1731270
Numéro CE :
203-539-1
Numéro MDL:
MFCD00004537
Code UNSPSC :
12352100
ID de substance PubChem :
57651153
Nomenclature NACRES :
NA.21

Densité de vapeur

3.12 (vs air)

Niveau de qualité

200

Pression de vapeur

10.9 mmHg ( 25 °C)

Gamme de produits

ReagentPlus®

Pureté

≥99.5%

Forme

liquid

Température d'inflammation spontanée

532 °F

Limite d'explosivité

13.8 %

Caractéristiques du produit alternatif plus écologique

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Impuretés

≤0.001% water

Indice de réfraction

n20/D 1.403 (lit.)

Point d'ébullition

118-119 °C (lit.)

Pf

-97 °C

Solubilité

water: miscible

Densité

0.916 g/mL at 25 °C (lit.)

Application(s)

microbiology

Autre catégorie plus écologique

, Aligned

Chaîne SMILES 

CC(O)COC

InChI

1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3

Clé InChI

ARXJGSRGQADJSQ-UHFFFAOYSA-N

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Catégories apparentées

Description générale

1-Methoxy-2-propanol (Propylene glycol methyl ether, PGME), a glycol ether, can be synthesized by reacting propylene oxide with methanol in the presence of ZnMgAl (zinc-magnesium-aluminium) catalysts. Its degradation by microorganisms in different soil types has been investigated. An oral reference dose (RfD) and an inhalation reference concentration (RfC) values of PGME have been obtained from inhalation studies in F344 rats and B6C3F1 mice.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry.Monoethers, especially propylene glycol methyl ether (PGME), are widely used as pollution-free solvents in fine chemical synthesis in pharmaceutical, chemical and cosmetic industries and thus aligns with "Safer Solvents and Auxiliaries". Click here for more information.

Informations légales

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

FlameExclamation mark
GHS02,GHS07

Mention d'avertissement

Warning

Mentions de danger

H226,H336

Classification des risques

Flam. Liq. 3 - STOT SE 3

Organes cibles

Central nervous system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

93.2 °F - closed cup

Point d'éclair (°C)

34 °C - closed cup

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificats d'analyse (COA)

Lot/Batch Number
STBL4198
MKCW2242
MKCW0598
MKCW1794
SDBB1290

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Sigma-Aldrich

E7401

3-Ethoxy-1-propanol

Propylene glycol propyl ether 99%

Sigma-Aldrich

424927

Propylene glycol propyl ether

Influence of acid-base properties of ZnMgAl-mixed oxides for the synthesis of 1-methoxy-2-propanol.
Cheng W, et al.
Applied Clay Science, 42(1), 111-115 (2008)
Biodegradation of glycol ethers in soil.
Gonsior SJ and West RJ.
Environmental Toxicology and Chemistry / Setac, 14(8), 1273-1279 (1995)
Rei Momose et al.
Organic letters, 15(8), 2010-2013 (2013-04-11)
Three new alkaloids, hyrtimomines A-C (1-3), were isolated from an Okinawan marine sponge Hyrtios sp. The structures of 1-3 were elucidated on the basis of spectroscopic analysis and application of a phenylglycine methyl ester (PGME) method. Hyrtimomines A (1) and
C R Kirman et al.
Risk analysis : an official publication of the Society for Risk Analysis, 25(2), 271-284 (2005-05-07)
Reference values, including an oral reference dose (RfD) and an inhalation reference concentration (RfC), were derived for propylene glycol methyl ether (PGME), and an oral RfD was derived for its acetate (PGMEA). These values were based on transient sedation observed
Catherine Tomicic et al.
Analytical and bioanalytical chemistry, 396(7), 2709-2714 (2010-02-16)
Glycol ethers still continue to be a workplace hazard due to their important use on an industrial scale. Currently, chronic occupational exposures to low levels of xenobiotics become increasingly relevant. Thus, sensitive analytical methods for detecting biomarkers of exposure are
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