Accéder au contenu
Merck
Toutes les photos(1)

Key Documents

View All Documentation

10634425001

Roche

Octyl β-D-glucopyranoside

non-ionic

Synonyme(s) :

n-Octyl glucoside, OGP

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Formule empirique (notation de Hill):
C14H28O6
Numéro CAS:
29836-26-8
Poids moléculaire :
292.37
Numéro Beilstein :
84118
Numéro MDL:
MFCD00063288
Code UNSPSC :
12352200
ID de substance PubChem :
329748920

Pureté

99% (GC)

Poids mol.

micellar avg mol wt 25,000
 292.4

Conditionnement

pkg of 10 g

Fabricant/nom de marque

Roche

Nombre d'agrégation

84

Technique(s)

dialysis: suitable

CMC

20-25 mM (20-25°C)

Température de transition

cloud point >100 °C

Conditions d'expédition

ambient

Chaîne SMILES 

CCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1

Clé InChI

HEGSGKPQLMEBJL-RKQHYHRCSA-N

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Description générale

1-O-n-Octyl-β-D-glucopyranoside, octylglucoside, is a detergent with an octyl chain as hydrophobic residue and glucose as hydrophilic part. It is a non-ionic, dialyzable, mild and non-denaturing detergent which is used for the solubilization, isolation and reconstitution of membrane proteins.

Application

N-Octylglucoside has been shown to increase the resolution of proteins in 2D gels. It is a mild and non-denaturing detergent for the solubilization and reconstitution of membrane proteins. N-Octylglucoside is easily removed by dialysis. N-Octylglucoside has been used in mass spectrometric immunoassay to homogenize MALDI (matrix assisted laser desorption/ionization) matrix draw and elution.
Détergent non ionique, dialysable, pour la solubilisation et l′isolement des protéines membranaires. Permet d′augmenter la résolution des protéines dans les gels 2D.

Qualité

Purity: 99% (from C), homogeneous (GC)

Ease of removal*: ++
CMC**: 14.5 mM at +25°C
Formula: C14H28O6

Notes préparatoires

Working concentration: 46 mM
Working solution: Solubility: > 50% (w/v) in double-dist. water, Tris-HCl 0.05 mol/l; pH7.4 or K-phosphate buffer 0.1 mol/l, pH 7.0 at 25 °C.
Storage conditions (working solution): Stability in Solution
A stock solution is stable at 2 to 8 °C for approx. 3 days. We would expect a long term stability of 6-12 months if stored frozen in portions at -15 to -25 °C, provided bacterial contamination is avoided.

Stockage et stabilité

Store at 15 to 25 °C. (Store dry!)

Autres remarques

For life science research only. Not for use in diagnostic procedures.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

W A Petri et al.
The Journal of biological chemistry, 254(11), 4313-4316 (1979-06-10)
The glycoprotein of vesicular stomatitis (VS) virus was selectively liberated from the virion membrane by the dialyzable nonionic detergent, beta-D-octylglucoside. The isolated viral glycoprotein could be rendered virtually free of phospholipid and detergent, under which conditions it formed tail-to-tail glycoprotein
Howard R Mellor et al.
The Biochemical journal, 374(Pt 2), 307-314 (2003-05-29)
The N-alkyl moiety of N-alkylated imino sugars is crucial for therapeutic activities of these compounds as inhibitors of glycosphingolipid (GSL) biosynthesis and as antivirals. The improved potency afforded by a long N-alkyl moiety is coincident with increased compound-induced cytotoxicity. Therefore
Olgica Trenchevska et al.
Journal of proteome research, 9(11), 5969-5973 (2010-09-09)
Protein biomarkers are essential in assessing pathogenic processes. The impetus for finding new biomarkers has been accelerated by the arrival of the "omics" technologies. However, equally important is the rediscovery of existing biomarkers with these new approaches as novel variants
Olgica Trenchevska et al.
Proteome science, 9(1), 19-19 (2011-04-12)
Post-translational modifications and genetic variations give rise to protein variants that significantly increase the complexity of the human proteome. Modified proteins also play an important role in biological processes. While sandwich immunoassays are routinely used to determine protein concentrations, they

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique