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Key Documents

AB3230

Sigma-Aldrich

Anti-Low Density Lipoprotein Antibody, copper oxidized

serum, Chemicon®

Synonyme(s) :

LDL

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

serum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

human

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... LDLR(3949)

Spécificité

Reacts strongly to fully oxidatized modifications of LDL including Cu2+-oxidized LDL, MDA-LDL, HOCL-LDL but not to other oxidized proteins like MDA-HSA, HOCL-HSA, MDA-HDL, HOCL-HDL (below detection limit). The reaction of native LDL was weak, but clearly detectable (approx. 20%). Minimally oxidized LDL gave a strong binding signal (>80%).

Immunogène

Epitope: copper oxidized
Fully Cu2+-oxidized LDL.

Application

Anti-Low Density Lipoprotein Antibody, copper oxidized is an antibody against Low Density Lipoprotein for use in ELISA, WB, IH.
Research Category
Metabolism
Research Sub Category
Lipid Metabolism & Weight Regulation
Western Blot

Immunohistochemistry: 1:50-1:500

ELISA: 1:500-1:5,000

Optimal working dilutions must be determined by the end user.

Forme physique

Rabbit serum. Lyophilized. Contains no preservative. Reconstitute with 100 μL of sterile distilled water.

Stockage et stabilité

Maintain lyophilized material at 2-8°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Tadashi Uramatsu et al.
Biological & pharmaceutical bulletin, 36(8), 1271-1277 (2013-08-02)
Stroke-prone spontaneously hypertensive (SHRsp) rats develop severe hypertension resulting in renal injury. We investigated apoptosis inhibitor of macrophages (AIM) expression in nephrosclerotic rats and the involvement of AIM in olmesartan (OLM)- and azelnidipine (AZN)-induced decreases in the number of macrophages
Deepa Sankaran et al.
Nephron. Experimental nephrology, 106(4), e122-e128 (2007-07-12)
Dietary soy protein and flax oil retard kidney disease progression when initiated in the early stages of disease in several experimental models, including the Han:SPRD-cy rat. However, individuals with kidney disease often do not become aware of their condition until
Deficiency in the metabolite receptor SUCNR1 (GPR91) leads to outer retinal lesions.
Favret, S; Binet, F; Lapalme, E; Leboeuf, D; Carbadillo, J; Rubic, T; Picard, E; Mawambo et al.
Aging null
Malcolm R Ogborn et al.
Lipids, 43(9), 783-791 (2008-07-17)
Conjugated linoleic acid (CLA) is anti-proliferative and anti-inflammatory in the Han:SPRD-cy rat model of kidney disease. We used different doses of CLA and examined effects on renal histological benefit, the renal PPARgamma system and hepatic and renal levels of CLA
Dietary soya protein during pregnancy and lactation in rats with hereditary kidney disease attenuates disease progression in offspring.
Cahill, LE; Peng, CY; Bankovic-Calic, N; Sankaran, D; Ogborn, MR; Aukema, HM
The British Journal of Nutrition null

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