489350

L-(–)-Norepinephrine-(+)-bitartrate

α,β-Adrenergic agonist.

• Synonyme(s) : L-(−)-Norepinephrine-(+)-bitartrate salt monohydrate, R(–)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol-(+)-tartrate, Noradrenaline
• Formule empirique (notation de Hill): C₈H₁₁NO₃ · C₄H₆O₆ · H₂O
• Numéro CAS: 108341-18-0
• Poids moléculaire : 337.28
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥97% (LC/MS)
• Forme: crystalline solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; desiccated
• Couleur: white
• Solubilité: water: 1 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: 2-8°C
• InChI: 1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t8-;1-,2-;/m01./s1
• Clé InChI: LNBCGLZYLJMGKP-LUDZCAPTSA-N

Description

Description générale

α,β-Adrenergic agonist. A vasoconstrictive agent that causes down-regulation of angiotensin II receptors.

α,β-Adrenergic agonist. A vasoconstrictive agent that causes down-regulation of angiotensin II receptors. Oxidation sensitive.

Actions biochimiques/physiologiques

Cell permeable: no

Primary Target
α,β-Adrenergic agonist

Product does not compete with ATP.

Reversible: no

Avertissement

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

Notes préparatoires

Addition of sodium bisulfite (at a final concentration of 0.1%) is necessary to prevent oxidation.

Reconstitution

Following reconstituiton, refrigerate (4°C). Stock solutions are stable for up to 5 days at 4°C.

Autres remarques

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Yang, H., et al. 1996. Hypertension 27, 1277.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H300 + H310
• Conseils de prudence: P262 - P264 - P280 - P301 + P310 - P302 + P352 + P310 - P361 + P364
• Classification des risques: Acute Tox. 1 Dermal - Acute Tox. 2 Oral
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable