481486

NF-κB SN50M, Cell-Permeable Inactive Control Peptide

An inactive control for SN50 peptide.

• Synonyme(s) : NF-κB SN50M, Cell-Permeable Inactive Control Peptide, (AAVALLPAVLLALLAPVQRNGQKLMP)
• Formule empirique (notation de Hill): C₁₂₃H₂₁₅N₃₃O₃₀S
• Poids moléculaire : 2668.29
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥97% (HPLC)
• Forme: lyophilized
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; desiccated (hygroscopic)
• Solubilité: water: 5 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: −20°C

Description

Description générale

An inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Asn for Lys³⁶³ and Gly for Arg³⁶⁴ in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM.

An inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Lys³⁶³ for Asn and Arg³⁶⁴ for Gly in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM.

Actions biochimiques/physiologiques

Cell permeable: no

Primary Target
an inactive control for SN50 peptide

Product does not compete with ATP.

Reversible: no

Conditionnement

Yes

Avertissement

Toxicity: Standard Handling (A)

Séquence

H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Asn-Gly-Gln-Lys-Leu-Met-Pro-OH

Forme physique

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid/freeze thaw cycles of solutions.

Autres remarques

Lin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.

Informations légales

Sold under license of U.S. Patents 5,807,746 and 6,043,339 for research use only. Licenses for commercial manufacture, commercial use, diagnostics, or therapeutics may be obtained by contacting Vanderbilt University, Nashville, Tennessee.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable