400120
Human IgG₁, Myeloma
Synonyme(s) :
Myeloma IgG₁
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About This Item
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.32
Produits recommandés
Pureté
>95% (SDS-PAGE)
Niveau de qualité
Forme
liquid
Contient
≤0.1% sodium azide as preservative
Fabricant/nom de marque
Calbiochem®
Conditions de stockage
OK to freeze
Conditions d'expédition
wet ice
Température de stockage
−20°C
Description générale
Native IgG1 from human myeloma plasma.
Native IgG1 from human myeloma plasma. Purified from plasma of patients with myelomas producing IgG1 with kappa light chains.
Avertissement
Toxicity: Standard Handling (A)
Forme physique
In 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.
Notes préparatoires
Prepared from plasma that was shown by certified tests to be negative for HBsAg and for antibodies to HCV, HBc, HIV-1 and HIV-2.
Autres remarques
Single arc by immunoelectrophoresis against antiserum to whole human sera and human κ free and bound light chain. Note: the heavy chain of myeloma IgGs may appear as either a single or double band on gel electrophoresis. Variables associated with assay conditions will dictate the proper working dilution.
Informations légales
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Liliane Khoryati et al.
Arthritis & rheumatology (Hoboken, N.J.), 68(9), 2221-2231 (2016-03-19)
Plasmacytoid dendritic cells (PDCs) play a central role in pathogenesis of systemic lupus erythematosus (SLE) through their unique ability to produce large amounts of type I interferon (IFN) upon Toll-like receptor 7 (TLR-7) and TLR-9 triggering. PDCs express specific surface
R B Cejas et al.
Scientific reports, 11(1), 10981-10981 (2021-05-28)
Persons with Down syndrome (DS, trisomy 21) have widespread cellular protein trafficking defects. There is a paucity of data describing the intracellular transport of IgG in the context of endosomal-lysosomal alterations linked to trisomy 21. In this study, we analyzed
Anna Moroz et al.
Bioconjugate chemistry, 29(10), 3476-3482 (2018-09-20)
The swell of experimental imaging technologies to noninvasively measure immune checkpoint protein expression presents the opportunity for rigorous comparative studies toward identifying a gold standard. 89Zr-atezolizumab is currently in man, and early data show tumor targeting but also abundant uptake
Lili Huang et al.
Journal of leukocyte biology, 80(4), 905-914 (2006-08-05)
LFA-1 (alpha(L)beta(2)) mediates cell-cell and cell-extracellular matrix adhesions essential for immune and inflammatory responses. One critical mechanism regulating LFA-1 activity is the conformational change of the ligand-binding alpha(L) I domain from low-affinity (LA), closed form, to the high-affinity (HA), open
Jorg C de Ruijter et al.
FEMS yeast research, 17(1) (2016-12-14)
Cost-effective manufacturing of biopharmaceuticals in non-mammalian hosts still requires tremendous efforts in strain development. In order to expedite identification of novel leads for strain engineering, we used a transposon-mutagenized yeast genomic DNA library to create a collection of Saccharomyces cerevisiae
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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