16-455
Anti-Phosphoserine Antibody, clone 4A4, HRP Conjugate
clone 4A4, Upstate®, from mouse
Synonyme(s) :
4A4, anti-phosphoserine, phosphoserine antibody, pan-phosphoserine
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Niveau de qualité
Conjugué
peroxidase conjugate
Forme d'anticorps
purified antibody
Type de produit anticorps
primary antibodies
Clone
4A4, monoclonal
Réactivité de l'espèce (prédite par homologie)
all
Fabricant/nom de marque
Upstate®
Technique(s)
western blot: suitable
Isotype
IgG1
Conditions d'expédition
wet ice
Modification post-traductionnelle de la cible
phosphorylation (pSer)
Description générale
The identification of protein phosphorylation as a regulatory mechanism originated from studies by Fischer and Krebs in the mid 1950s that later earned them the 1992 Nobel prize. It is the major mechanism for the regulation of diverse cellular processes including cell division, protein synthesis, transcriptional regulation and neurotrans-mission. The steady state phosphorylation of any given substrate is governed by the opposing activities of kinases and phosphatases. It is now believed that a third of all eukaryotic cellular proteins are phosphorylated and that over 95% of all phosphorylation events occur on serine and threonine residues.
Spécificité
Recognizes proteins containing phosphoserine residues, regardless of origin.
Immunogène
Epitope: phosphoserine
Phosphoserine conjugated to KLH.
Application
Anti-Phosphoserine Antibody, clone 4A4, HRP Conjugate is an antibody against Phosphoserine for use in WB.
Research Category
Signaling
Signaling
Research Sub Category
General Post-translation Modification
General Post-translation Modification
Qualité
Routinely evaluated by western blot on RIPA lysates from insulin-treated human HEK293 cells.
Description de la cible
Varies
Forme physique
100 μL of protein G purified mouse IgG1 in PBS containing 0.05% Kathon® and HRP stabilizing compounds. Sufficient for a minimum of 10 immunoblots, if used at the optimum concentration of 1:4000 in 10 mL blocking buffer. Liquid.
Protein G Purified
Stockage et stabilité
6 months at 2-8°C from date of shipment.
NOTE: DO NOT FREEZE. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NOTE: DO NOT FREEZE. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Informations légales
Kathon is a registered trademark of Rohm and Haas Co.
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Certificats d'analyse (COA)
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