P-120

Prégabaline solution

10.0 mg/mL in water, ampule of 1 mL, certified reference material, Cerilliant^®

• Formule empirique (notation de Hill): C₈H₁₇NO₂
• Numéro CAS: 148553-50-8
• Poids moléculaire : 159.23
• Numéro MDL: MFCD00906155
• Code UNSPSC : 41116107
• ID de substance PubChem : 329820077
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Niveau de qualité: 300
• Forme: liquid
• Caractéristiques: Snap-N-Spike^®/Snap-N-Shoot^®
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• Contrôle du médicament: USDEA Schedule V
• Concentration: 10.0 mg/mL in water
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): clinical testing
• Format: single component solution
• Température de stockage: 2-8°C
• Chaîne SMILES: CC(CC([H])(CN)CC(O)=O)C
• InChI: 1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)
• Clé InChI: AYXYPKUFHZROOJ-UHFFFAOYSA-N

Description

Description générale

Pregabalin, marketed as the anticonvulsant drug Lyrica, is used in the treatment of epilepsy and generalized anxiety disorder. Along with other anticonvulsants such as gabapentin and levetiracetam, pregabalin is also used to treat neuropathic pain. This certified reference standard is suitable for pregabalin GC/MS or LC/MS applications from forensic analysis, clinical toxicology and pain prescription monitoring to urine drug testing.

Application

• An artifactual solution degradant of pregabalin due to adduct formation with acetonitrile catalyzed by alkaline impurities during HPLC sample preparation.: This study highlights the challenges in analytical chemistry, particularly the artifact formation in pregabalin solutions under specific conditions, emphasizing the need for rigorous control in pharmaceutical analysis to ensure product stability and efficacy (Lin et al., 2019).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable