850166P

18:0-20:4 PI(3,4,5)P3

1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt), powder

• Synonyme(s) : 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-[phosphoinositol-3,4,5-trisphosphate] (ammonium salt); PIP3[3′,4′,5′](18:0/20:4(5Z,8Z,11Z,14Z))
• Formule empirique (notation de Hill): C₄₇H₉₈N₄O₂₂P₄
• Numéro CAS: 799268-60-3
• Poids moléculaire : 1195.19
• Code UNSPSC : 51191904
• Nomenclature NACRES : NA.25

Propriétés

• Pureté: >99% (TLC)
• Forme: powder
• Conditionnement: pkg of 1 × 100 μg (with stopper and crimp cap (850166P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850166P-500ug))
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 850166P
• Type de lipide: phospholipids; cardiolipins
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+].[NH4+]

Description

Description générale

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Application

18:0-20:4 PI(3,4,5)P3 or 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt) has been used in:

• liposomes for liposome-pelleting assay to identify the binding preference of FCH and double SH3 domains protein (FCHSD2) for specific phosphoinositide
• liposomes to study specific protein-lipid interactions
• host 1-O-1-(Z)-octadecenyl-2-arachidonoyl-sn-glycero-3-phosphocholine (plasmenyl-SAPC) small unilamellar vesicles (SUVs) in the presence of H₂O₂ to activate cyt c plasmalogenase activity

Conditionnement

2 mL Amber Serum Vial with Stopper and Crimp Cap (850166P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850166P-500ug)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids