700149P
Avanti
16:0 cholesteryl-d7 ester
Avanti Research™ - A Croda Brand 700149P, powder
Synonyme(s) :
cholesteryl-d7 palmitate
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About This Item
Formule empirique (notation de Hill):
C43H69D7O2
Numéro CAS:
Poids moléculaire :
632.11
Code UNSPSC :
41141804
Nomenclature NACRES :
NA.25
Produits recommandés
Pureté
>99% (TLC)
Forme
powder
Conditionnement
pkg of 1 × 10 mg (700149P-10mg)
pkg of 1 × 25 mg (700149P-25mg)
Fabricant/nom de marque
Avanti Research™ - A Croda Brand 700149P
Conditions d'expédition
dry ice
Température de stockage
−20°C
Description générale
Cholesteryl palmitate is a cholesteryl ester. 16:0 cholesteryl-d7 ester is the deuterated form of cholesteryl palmitate or 16:0 cholesteryl ester.
Application
16:0 cholesteryl-d7 ester has been used:
- in plasma sample preparation for tandem mass spectrometry analysis (MS/MS)
- as an internal standard in mass spectrometry for quantification of nerve lipids from mice
- as an internal standard in time-of-flight mass spectrometry (TOFMS) for the quantification of serum extracellular vesicles (EVs) lipids
- as an external calibrator and internal spiking standard in tandem mass spectroscopy measurements
- in liposome preparation for retinyl ester hydrolase (REH) and cholesteryl esterase activity assay
Actions biochimiques/physiologiques
Cholesteryl palmitate is associated with atherosclerotic plaque. Deuterated cholesteryl palmitate in used in reconstituting high-density lipoprotein (HDL). An elevated levels of the ratio of cholesteryl oleate to cholesteryl palmitate is implicated with apoptotic cell death in the atherosclerotic lesions.
Conditionnement
5 mL Amber Glass Screw Cap Vial (700149P-10mg)
5 mL Amber Glass Screw Cap Vial (700149P-25mg)
Informations légales
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Souvent commandé avec ce produit
Réf. du produit
Description
Tarif
Code de la classe de stockage
11 - Combustible Solids
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Suming Chen et al.
Journal of circulating biomarkers, 8, 1849454419879848-1849454419879848 (2019-10-22)
There is a wide variety of extracellular vesicles (EVs) that differ in size and cargo composition. EVs isolated from human plasma or serum carry lipid, protein, and RNA cargo that provides insights to the regulation of normal physiological processes, and
Y I Parmar et al.
The Journal of biological chemistry, 258(3), 2000-2004 (1983-02-10)
Reconstituted high density lipoprotein has been prepared by sonication and preparative ultracentrifugation of mixtures containing the apoprotein of high density lipoprotein, egg phosphatidylcholine, cholesteryl oleate, and acyl chain deuterated cholesteryl palmitate in aqueous buffer. The resulting structures have a size
Michael S Gardner et al.
Journal of the American Society for Mass Spectrometry, 28(11), 2319-2329 (2017-08-13)
We demonstrate the application of in-source nitrogen collision-induced dissociation (CID) that eliminates the need for ester hydrolysis before simultaneous analysis of esterified cholesterol (EC) and triglycerides (TG) along with free cholesterol (FC) from human serum, using normal phase liquid chromatography
Y Zang et al.
Journal of dairy science, 102(2), 1224-1236 (2018-11-26)
Co-supplementation of methyl donors may lower hepatic lipid content in transition cows. To define the ability of methyl donor supplementation (MDS) to reduce hepatic lipid content and modify the plasma lipidome, 30 multiparous Holstein cows (2.04 ± 0.69 lactations; 689
Maidina Tuohetahuntila et al.
The Journal of biological chemistry, 292(30), 12436-12448 (2017-06-16)
Activation of hepatic stellate cells (HSCs) is a critical step in the development of liver fibrosis. During activation, HSCs lose their lipid droplets (LDs) containing triacylglycerols (TAGs), cholesteryl esters, and retinyl esters (REs). We previously provided evidence for the presence
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