P8533

Tributylammonium pyrophosphate

• Synonyme(s) : N,N-dibutyl-1-butanamine diphosphate
• Numéro CAS: 5975-18-8
• Numéro MDL: MFCD00136019
• Code UNSPSC : 12352116
• ID de substance PubChem : 329820329
• Nomenclature NACRES : NA.22

Propriétés

• Forme: powder
• Température de stockage: −20°C
• Chaîne SMILES: OP(O)(=O)OP(O)(O)=O.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC
• InChI: 1S/2C12H27N.H4O7P2/c2*1-4-7-10-13(11-8-5-2)12-9-6-3;1-8(2,3)7-9(4,5)6/h2*4-12H2,1-3H3;(H2,1,2,3)(H2,4,5,6)
• Clé InChI: WRMXOVHLRUVREB-UHFFFAOYSA-N

Description

Description générale

Tributylammonium pyrophosphate is a phosphorylating reagent used in the synthesis of modified dNTPs (deoxynucleoside triphosphates) which are important building blocks for the generation of DNA, RNA, functionalized nucleic acids.

Application

Reactant for:

• Enzymic synthesis of 3′-deoxy-apio-nucleic acid duplexes
• Synthesis of deoxynucleoside S-methylphosphonic acids
• Preparation of fluorescent non-nucleotide ATP analog N-methylanthraniloylamideethyl triphosphate

Tributylammonium pyrophosphate used as a phosphorylating reagent:

• In the synthesis of S′-deoxy-S′-methylphosphonic acid diphosphate along with 1, 1′-carbonyl diimidazole.
• In the synthesis of gram-scale level base-modified ribonucleoside-5′-O-triphosphates.
• In one-pot chemical synthesis of 2′-deoxynucleoside-5′-triphosphates with better protection.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)