910813

mPEG₂₄-NHS

• Synonyme(s) : Methoxypolyethylene glycol acetic acid N-succinimidyl ester, mPEG NHS
• Formule empirique (notation de Hill): C₅₆H₁₀₇NO₂₉
• Numéro CAS: 174569-25-6
• Poids moléculaire : 1258.44
• Numéro MDL: MFCD28385538
• Code UNSPSC : 43211915
• Nomenclature NACRES : NA.23

Propriétés

• Pureté: 95% (HPLC)
• Forme: solid
• Poids mol.: average M_n 1,250 (by NMR)
• Pertinence de la réaction: reagent type: chemical modification reagent; reactivity: amine reactive
• Couleur: white to off-white
• Extrémité Ω: NHS ester
• Extrémité α: methoxy
• Architecture des polymères: shape: linear; functionality: monofunctional
• Température de stockage: −20°C

Description

Application

Polyethylene glycols (PEGs) are FDA approved hydrophilic polymers. They are non-toxic, non-immunogenic and non-antigenic, and are widely used in a variety of biomedical applications such as bioconjugation, drug delivery, surface functionalization, and tissue engineering. PEG-NHS is an amine reactive PEG that can react to amino groups of lysine(s) on proteins or other biologics; reaction occurs at room temperature in <1hr at pH 7-8. Stable linker between PEG and NHS ester.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): >230.0 °F
• Point d'éclair (°C): > 110 °C