679585

4-Methoxybenzyl-2,2,2-trichloroacetimidate

• Synonyme(s) : p-Methoxybenzyl trichloroacetimidate
• Formule empirique (notation de Hill): C₁₀H₁₀Cl₃NO₂
• Numéro CAS: 89238-99-3
• Poids moléculaire : 282.55
• Numéro MDL: MFCD00134547
• Code UNSPSC : 12352101
• ID de substance PubChem : 24885502
• Nomenclature NACRES : NA.22

Propriétés

• Impuretés: Major impurity is Trichloroacetamide by GCMS.
• Indice de réfraction: n20/D 1.5488
• Point d'ébullition: 135-137 °C/0.7 mmHg
• Densité: 1.361 g/mL at 25 °C
• Température de stockage: 2-8°C
• Chaîne SMILES: COc1ccc(COC(=N)C(Cl)(Cl)Cl)cc1
• InChI: 1S/C10H10Cl3NO2/c1-15-8-4-2-7(3-5-8)6-16-9(14)10(11,12)13/h2-5,14H,6H2,1H3
• Clé InChI: TYHGKLBJBHACOI-UHFFFAOYSA-N

Description

Application

4-Methoxybenzyl-2,2,2-trichloroacetimidate can be used as a reagent for the protection of alcohols as the p-methoxybenzyl ether. 1^o, 2^o, and 3^o alcohols can be easily protected using this reagent with equal efficiency in the presence of a variety of different protective groups. This reagent is commonly used under acidic conditions therefore it offers an alternative method to the Williamson ether synthesis, which is typically used basic conditions to protect base-sensitive alcohols.

Informations sur la sécurité

• Pictogrammes: GHS07,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H302 + H312 + H332,H315,H319,H335,H411
• Conseils de prudence: P273 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): >230.0 °F
• Point d'éclair (°C): > 110 °C