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235202

Sigma-Aldrich

4-Bromomethyl-7-methoxycoumarin

97%

Synonyme(s) :

BMC, Br-Mmc

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About This Item

Formule empirique (notation de Hill):
C11H9BrO3
Numéro CAS:
35231-44-8
Poids moléculaire :
269.09
Numéro Beilstein :
187211
Numéro CE :
252-448-3
Numéro MDL:
MFCD00006869
Code UNSPSC :
12352100
ID de substance PubChem :
24854087
Nomenclature NACRES :
NA.22

Pureté

97%

Forme

solid

Pf

213-215 °C (lit.)

Solubilité

chloroform: soluble 20 mg/mL, clear, colorless to faintly yellow

Fluorescence

λex 322 nm; λem 395 nm (after derivatization)

Chaîne SMILES 

COc1ccc2C(CBr)=CC(=O)Oc2c1

InChI

1S/C11H9BrO3/c1-14-8-2-3-9-7(6-12)4-11(13)15-10(9)5-8/h2-5H,6H2,1H3

Clé InChI

CTENSLORRMFPDH-UHFFFAOYSA-N

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Application

4-Bromomethyl-7-methoxycoumarin has been used:
  • as derivatization reagent in determination of 5-fluorouracil (5-FU) in human plasma by HPLC-tandem mass spectrometry
  • as derivatization reagent in fluorescence detection of sodium monofluoroacetate (MFA-Na) in biological samples by HPLC
  • in the synthesis of new caged derivatives of hydrolysis-resistant 8-bromoadenosine cyclic 3′,5′-monophosphate (8-Br-cAMP) and 8-bromoguanosine cyclic 3′,5′-monophosphate (8-Br-cGMP)
  • in TLC and HPLC separation and fluorometric analysis of a wide range of naturally occurring acids, including bile and thromboxane B2
Fluorescent label for fatty acids.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302,H315,H319,H335

Classification des risques

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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