444212

MMP-2 Substrate, Fluorogenic

A quenched fluorescence substrate for MMP-2 (gelatinase A; k_cat/Km = 3.97 x 10⁵ M⁻¹s⁻¹).

• Synonym(s): MMP-2 Substrate, Fluorogenic
• Empirical Formula (Hill Notation): C₄₉H₆₈N₁₄O₁₅
• Molecular Weight: 1093.15
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥95% (HPLC)
• form: lyophilized solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated; protect from light
• color: yellow
• solubility: DMSO: 10 mg/mL
• fluorescence: λ_ex ~325 nm; λ_em ~393 nm
• shipped in: ambient
• storage temp.: −20°C

Description

General description

A quenched fluorescence substrate for MMP-2 (gelatinase A; k_cat/K_m = 3.97 x 10⁵ M^-1s^-1).

A quenched fluorescence substrate for MMP-2 (gelatinase A; k_cat/K_m = 3.97 x 10⁵ M^-1s^-1; excitation maximum: ~325 nm; emission maximum: ~393 nm).

Biochem/physiol Actions

Cell permeable: no

Primary Target
A quenched fluorescence substrate for MMP-2 (gelatinase A)

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

MCA-Pro-Leu-Ala-Nva-Dpa-Ala-Arg-NH₂[Dpa = 3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl; Nva = L-norvaline]

Other Notes

Murphy, G., et al. 1994. J. Biol. Chem. 269, 6632.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable