A New Derivatization Reagent for HPLC-MS Analysis of Biological Organic Acids.

A New Derivatization Reagent for HPLC-MS Analysis of Biological Organic Acids.

Chromatographia (2017-12-08)

Bryce J Marquis, Hayley P Louks, Chhanda Bose, Robert R Wolfe, Sharda P Singh

RÉSUMÉ

Small molecules containing carboxylic acid functional groups are ubiquitous throughout biology, playing vital roles in biological chemistry ranging from energy metabolism to cellular signaling. This paper describes a new derivatization reagent, 4-bromo-

MATÉRIAUX

Référence du produit

Marque

Description du produit

39391

Sigma-Aldrich

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide, ≥97.0% (T)

291145

Sigma-Aldrich

N-Ethylmethylamine, 97%

M54058

Sigma-Aldrich

Methylmalonic acid, 99%