- Combinatorial libraries of bis-heterocyclic compounds with skeletal diversity.
Combinatorial libraries of bis-heterocyclic compounds with skeletal diversity.
Journal of combinatorial chemistry (2008-09-25)
Miroslav Soural, Isabelle Bouillon, Viktor Krchnák
PMID18811208
RÉSUMÉ
Combinatorial solid-phase synthesis of bis-heterocyclic compounds, characterized by the presence of two heterocyclic cores connected by a spacer of variable length/structure, provided structurally heterogeneous libraries with skeletal diversity. Both heterocyclic rings were assembled on resin in a combinatorial fashion.