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[The calcipotriol-betamethasone dipropionate association].

Revue medicale de Liege (2006-01-13)
F Henry, C Flagothier, P Delvoye, C Piérard-Franchimont, G E Piérard
RÉSUMÉ

The topical treatment of psoriasis benefits from the alternate use of dermocorticosteroids and vitamin D3 analogues. A new galenic formulation allows to combine them in a single application. Dovobet (LEO Pharma) ointment is the association of calcipotriol 50 microg/g with betamethasone dipoprionate 0.5 mg/g. This formulation boosts the therapeutic activity of calcipotriol. It also decreases the irritative inflammatory reaction due to calcipotriol without increasing the atrophogenic risk of the dermocorticoid.

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Sigma-Aldrich
Betamethasone, ≥98%
USP
Betamethasone dipropionate, United States Pharmacopeia (USP) Reference Standard
Supelco
Betamethasone Dipropionate, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
Betamethasone, Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
Betamethasone 17,21-dipropionate
Supelco
Betamethasone, VETRANAL®, analytical standard
Betamethasone dipropionate, European Pharmacopoeia (EP) Reference Standard
Betamethasone, European Pharmacopoeia (EP) Reference Standard
Betamethasone dipropionate for peak identification, European Pharmacopoeia (EP) Reference Standard