In vivo and in vitro studies on the binding nature of terreic acid with macromolecules such as protein and nucleic acids.

The binding of terreic acid to macromolecules such as nucleic acids and protein was examined. In vivo studies using [14C]terreic acid showed that radioactivity was incorporated into the protein and nucleic acid fractions of the liver mice. In vitro experiments with human serum showed that [14C]terreic acid bound to the albumin component and spectral studies indicated that terreic acid also combined with hepatic DNA.