- Investigation of the impurities found in methamphetamine synthesised from pseudoephedrine by reduction with hydriodic acid and red phosphorus.
Investigation of the impurities found in methamphetamine synthesised from pseudoephedrine by reduction with hydriodic acid and red phosphorus.
Forensic science international (1995-12-18)
K L Windahl, M J McTigue, J R Pearson, S J Pratt, J E Rowe, E M Sear
PMID8566917
RÉSUMÉ
The synthesis of methamphetamine from pseudoephedrine via the reduction with hydriodic acid and red phosphorus was studied and the impurities which were generated, along with the methamphetamine, were investigated. Some of the impurities found have been reported previously, while the diastereoisomers of N-methyl-N-(alpha- methylphenethyl)amino-1-phenyl-2-propanone and the cis-cinnamoyl derivative of methamphetamine are reported here for the first time. Further work on the sequence of reactions occurring in this reduction is also reported.
MATÉRIAUX
Référence du produit
Marque
Description du produit
Sigma-Aldrich
Hydriodic acid, contains no stabilizer, distilled, 57 wt. % in H2O, 99.99% trace metals basis
Sigma-Aldrich
Hydriodic acid, contains ≤1.5% hypophosphorous acid as stabilizer, ACS reagent, ≥47.0%