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[Cardiovascular adverse effects due to phenylephrine eye drops in ophtalmic surgery].

Annales francaises d'anesthesie et de reanimation (2013-02-05)
S Kauffmann, F Commun, P Schoeffler, G Souteyrand, F Chiambaretta, P Dewachter
RÉSUMÉ

Adverse systemic reactions such as cardiovascular effects may occur following topical ocular application of phenylephrine. We report the case of a 49-year-old woman who, following topical application of phenylephrine eyedrops, experienced hypertension with electrocardiographic modifications and a rise in cardiac troponin Ic.

MATÉRIAUX
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Description du produit

Sigma-Aldrich
(R)-(−)-Phenylephrine hydrochloride, powder
Supelco
Phenylephrine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
R-(-)-Phenylephrine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
Phenylephrine hydrochloride for peak identification, European Pharmacopoeia (EP) Reference Standard
Sigma-Aldrich
(R)-(−)-Phenylephrine hydrochloride, analytical standard