- Stereocontrolled access to optically-enriched oxabispidines.
Stereocontrolled access to optically-enriched oxabispidines.
Chemical communications (Cambridge, England) (2012-04-14)
Heloise Brice, Duncan M Gill, Laura Goldie, Philip S Keegan, William J Kerr, Per H Svensson
PMID22499212
RÉSUMÉ
A range of chiral, optically-enriched bicyclic oxabispidines were prepared from (S)-(-)-2,3-epoxypropylphthalimide using an efficient sequence featuring a stereocontrolled intramolecular Mannich reaction as the key transformation.