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Spurious azotemia associated with 5-fluorocytosine therapy.

Urology (1990-09-01)
S M Colagiovanni, E M Meares, G R Sant
RÉSUMÉ

A patient with false elevation of serum creatinine level due to 5-fluorocytosine (5-FC) is reported. 5-FC interferes with the enzymatic method used for creatinine determination in the Kodak Ektachem analyzer. Clinicians should be aware of the potential for spurious azotemia in patients receiving 5-FC therapy for fungal urinary tract infections.

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Sigma-Aldrich
Creatinine Deiminase microbial, lyophilized powder, ≥25 units/mg protein