Assignment of the human renal dipeptidase gene (DPEP1) to band q24 of chromosome 16.

Assignment of the human renal dipeptidase gene (DPEP1) to band q24 of chromosome 16.

Cytogenetics and cell genetics (1992-01-01)

H Nakagawa, J Inazawa, K Inoue, S Misawa, K Kashima, H Adachi, H Nakazato, T Abe

RÉSUMÉ

Renal dipeptidase (DPEP1) or dehydropeptidase-I (E.C.3.4.13.11) is a kidney membrane enzyme which hydrolyzes a variety of dipeptides. DPEP1 is implicated in the renal metabolism of glutathione and its conjugates and is also responsible for hydrolysis of beta-lactam antibiotics. Using a human DPEP1 cDNA probe, we mapped the human renal dipeptidase gene to human chromosome 16 at band q24 by in situ hybridization.