C7017

Chlorure de choline

≥99%

• Synonyme(s) : Chlorure de (2-hydroxyéthyl)triméthylammonium
• Formule linéaire : (CH₃)₃N(Cl)CH₂CH₂OH
• Numéro CAS: 67-48-1
• Poids moléculaire : 139.62
• Numéro Beilstein : 3563126
• Numéro CE : 200-655-4
• Numéro MDL: MFCD00011721
• Code UNSPSC : 50501514
• ID de substance PubChem : 57654039
• Nomenclature NACRES : NA.25

Propriétés

• Source biologique: synthetic
• Pureté: ≥99%
• Forme: powder
• Couleur: white
• Pf: 302-305 °C (dec.) (lit.)
• Type de lipide: phospholipids
• Chaîne SMILES: [Cl-].C[N+](C)(C)CCO
• InChI: 1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
• Clé InChI: SGMZJAMFUVOLNK-UHFFFAOYSA-M

Description

Description générale

Choline is a constituent of sphingomyelin and lecithin. It is a precursor of acetylcholine. Choline plays a vital role in methyl group metabolism, carcinogenesis and lipid transport. Choline deficiency is associated with fatty liver. It maintains cell structural integrity and cell signalling. Choline is implicated in the synthesis of phospholipids. It acts as a potent biomarker for ischemic heart disease.

Application

Choline chloride has been used:

• in choline release assay
• as an endogenous agonist of sigma-1 receptors (Sig-1Rs)
• as a standard to analyse interrelationships between methionine and choline metabolism

Actions biochimiques/physiologiques

Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes.

Substrats

Substrat de la choline acétyltransférase

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves