C3506

Cytosine

≥99%

• Synonyme(s) : 4-Amino-2-hydroxypyrimidine, 4-Aminopyrimidin-2-(1H)-one
• Formule empirique (notation de Hill): C₄H₅N₃O
• Numéro CAS: 71-30-7
• Poids moléculaire : 111.10
• Numéro Beilstein : 2637
• Numéro CE : 200-749-5
• Numéro MDL: MFCD00006034
• Code UNSPSC : 41106305
• ID de substance PubChem : 24892620
• Nomenclature NACRES : NA.51

Propriétés

• Source biologique: synthetic (organic)
• Pureté: ≥99%
• Forme: powder
• Pf: >300 °C (lit.)
• Solubilité: 0.5 M HCl: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
• Chaîne SMILES: NC1=NC(=O)NC=C1
• InChI: 1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)
• Clé InChI: OPTASPLRGRRNAP-UHFFFAOYSA-N

Description

Application

Cytosine has been used:

• for the preparation of nucleobase solutions
• as a standard for high-performance liquid chromatography (HPLC)
• for the estimation of global methylation rate
• for nucleoside 5′-triphosphate (NTP) synthesis
• purification

Actions biochimiques/physiologiques

Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).

Cytosine is a pyrimidine, which forms three hydrogen bonds to base pair with guanine. It forms a nucleotide cytidine, that is phosphorylated to cytidine 5′ monophosphate (CMP), cytidine 5′ diphosphate (CDP) and cytidine 5′ triphosphate (CTP).

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves