407294

αA-Interferon, Human, Recombinant, E. coli

• Synonyme(s) : IFNA2A, IFNA2B, IFNA2C, rhIFN-αA
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.77

Propriétés

• Pureté: ≥95% (SDS-PAGE)
• Niveau de qualité: 100
• Forme: liquid
• Activité spécifique: ≥2.8 x 10⁸ units/mg protein; ≥5 x 10⁶ units/mL
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; avoid repeated freeze/thaw cycles
• Technique(s): cell based assay: suitable
• Numéro d'accès NCBI: NM_000605.4
• Numéro d'accès UniProt: P01563
• Conditions d'expédition: wet ice
• Température de stockage: −70°C
• Informations sur le gène: human ... IFNA1(3340)

Description

Description générale

Note: 1 MU = 1,000,000 units.

Recombinant, human αA-interferon expressed in E. coli. Antiviral, anti-neoplastic agent. αA-Interferon exhibits therapeutic potential in chronic viral hepatitis, polycythemia vera, and various malignancies. It enhances natural killer cell activity, suppresses bone marrow function, and induces apoptotic cell death in non-melanoma skin cancer.

Recombinant, human αA-interferon expressed in E. coli. Antiviral, anti-neoplastic agent. αA-Interferon exhibits therapeutic potential with chronic viral hepatitis, polycythemia vera, and various malignancies. It enhances natural killer cell activity, suppresses bone marrow function, and induces apoptotic cell death in non-melanoma skin cancer. NOTE: 1MU = 1,000,000 units.

Avertissement

Toxicity: Standard Handling (A)

Définition de l'unité

One unit of interferon per ml of medium will cause a 50% inhibition of VSV-induced cytopathic effect on bovine MDBK cells. Units are determined with respect to the NIH international reference standard for human αA-IFN. Dilute in aqueous buffer containing at least 0.1% BSA or HSA.

Forme physique

In PBS containing 0.1% BSA.

Notes préparatoires

Dilute only in buffers containing protein such as 0.1% BSA.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Autres remarques

Fujishima, H., et al. 1998. Int. J. Cancer 76, 423.
Haria, M., and Benfield, P. 1995. Drugs 50, 873.
Familletti, P.C., et al. 1981. Methods Enzymol. 78, 387.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable