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Anti-KA2/GRIK5 (Kainate Receptor) Antibody

Upstate®, from rabbit

Synonyme(s) :

Anti-EAA2, Anti-GRIK2, Anti-GluK5, Anti-KA2

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

rat, rabbit

Fabricant/nom de marque

Upstate®

Technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotype

IgG

Numéro d'accès NCBI

NM_017262
NM_031508

Numéro d'accès UniProt

Q16478

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... GRIK5(2901)

Spécificité

KA2

Immunogène

21 residue synthetic peptide (KTSPPRPRPGPTGPRELTEHE) corresponding to the c-terminus of rat KA2 with a lysine added to the n-terminus

Application

Anti-KA2/GRIK5 (Kainate Receptor) Antibody is an antibody against KA2/GRIK5 (Kainate Receptor) for use in IC, IH, IP & WB.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins

Neurodegenerative Diseases

Qualité

routinely evaluated by immunoblot on rat brain microsomal preparation

Description de la cible

123kDa

Forme physique

Format: Purified
Protein G Chromatography
of 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%

Stockage et stabilité

2 years at -20°C

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

S Mehta et al.
The Journal of biological chemistry, 276(19), 16092-16099 (2001-03-30)
Recent studies have demonstrated that kainate receptors are associated with members of the SAP90/PSD-95 family (synapse-associated proteins (SAPs)) in neurons and that SAP90 can cluster and modify the electrophysiological properties of GluR6/KA2 kainate receptors when co-expressed in transfected cells. In
Functional cooperation between KA2 and GluR6 subunits is involved in the ischemic brain injury.
Hai-Xia Jiang, Qiu-Hua Guan, Dong-Sheng Pei, Guang-Yi Zhang
Journal of Neuroscience Research null
Sanja Selak et al.
Neuron, 63(3), 357-371 (2009-08-15)
Regulation of surface insertion and internalization of AMPA and NMDA receptors has emerged as a key mechanism for the control of synaptic strength. Regulatory elements for synaptic kainate receptors (KARs) are, however, largely undetermined. We have found that SNAP25 is
E P Garcia et al.
Neuron, 21(4), 727-739 (1998-11-10)
The mechanism of kainate receptor targeting and clustering is still unresolved. Here, we demonstrate that members of the SAP90/PSD-95 family colocalize and associate with kainate receptors. SAP90 and SAP102 coimmunoprecipitate with both KA2 and GluR6, but only SAP97 coimmunoprecipitates with
Synaptic expression of the high-affinity kainate receptor subunit KA2 in hippocampal cultures
Roche, K. W. and Huganir, R. L.
Neuroscience, 69, 383-393 (1995)
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