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TRAF3

TNF receptor-associated factor 3

Synonymes:
CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(7187) Summary: The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010]
  • Mouse(22031) TNF receptor-associated factor 3
  • Rat(362788) Tnf receptor-associated factor 3
  • cow(506182) TNF receptor-associated factor 3
  • dog(490867) TNF receptor-associated factor 3
  • chicken(423471) TNF receptor-associated factor 3
  • Zebrafish(445119) TNF receptor-associated factor 3
  • naked mole-rat(101718736) TNF receptor-associated factor 3
  • domestic guinea pig(100734492) TNF receptor-associated factor 3
  • sheep(100036758) TNF receptor-associated factor 3
  • domestic cat(101096739) TNF receptor-associated factor 3
  • Horse(100055110) TNF receptor-associated factor 3

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-TRAF3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-TRAF3 antibody produced in mouse, clone 1C5, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
proximity ligation assay

western blot
Anti-TRAF3 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse
Application
ELISA
immunofluorescence

western blot
Anti-TRAF3, from rabbit, purified by affinity chromatography,
Espèces réactives
bovine, horse, human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human TRAF3,
Espèce(s)
human